Ostarine Ostabolic (MK2866)

ostarine (MK2866) review


Ostarine Ostabolic (MK2866), also called Enobosarm, is a SARM (selective androgen receptor modulator) currently in clinical testing.   It is being developed by GTX Inc (formerly Merck) to treat muscle wasting and osteoporosis (bone disease).    The goal is to provide the elderly with a safe treatment for their conditions, replacing harsher hormones or drugs.  Those in fitness have realized its potential, and in the past 5 years have rapidly started using it as a low side effect performance enhancer.

What it does

Ostarine Ostabolic (MK2866) does what other SARMS (selective androgen receptor modulators) do, which is bind directly to androgen receptors.  Anabolic steroids do the same thing, however, Ostarine Ostabolic (MK2866) will not convert to estrogen or dihydrotestosterone (DHT).   Instead, it provides direct anabolic activity, which results in clean muscle growth when in an anabolic state; and a prevention of muscle wasting, when the body is catabolic.  (more on this later)


Ostarine Ostabolic (MK2866) has undergone at least 8 scientific trials, using over 500 subjects, which have shown promising results.   A recent study was done on 120 healthy elderly men, who were over 60 years old, and postmenopausal women.   The goal was to see how well it did with muscle wasting (cachexia), which is a metabolic condition that involves loss of skeletal muscle and a physical function decline.  There are several muscle wasting diseases including cacner, pulmonary disease, renal disease, and other chronic issues.

The endpoint monitored total lean body mass via Xray absorptiometry, and there was a monitor of secondary endpoints like body weight, insulin resistance, and body function.

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Total lean body mass gain %

The results were as follows:

  1.  Total lean body mass rose depending on dosage
  2. Physical function was improved significantly
  3. Insulin resistance decreased
  4. No adverse side effects were observed


Athletic uses

Ostarine Ostabolic (MK2866) will increase nitrogen retention and protein synthesis, but does this by being very tissue specific.  This is why weightlifters report that it is good at healing joints.  You can also expect an overall boost in lean muscle mass, moderate strength gains, some fat loss, and an overall physical and mental well being.

It also does a great job of converting to anabolism in the muscle tissue and bone, this will mean you suffer less injuries when weight training.  In fact, users have reported they can push their bodies more and notice less nagging injuries.  This makes Ostarine Ostabolic (MK2866) a great choice for the hardcore weightlifters, whether you lift super heavy, or you do super sets with a lot of volume.  Expect less injuries when using it!

Best ways to stack


Ostarine Ostabolic (MK2866) is fantastic in a cutting phase because you can be in a caloric deficit (catabolic state) and still keep your muscle while burning away fat.  It works great in a stack at 25-50mg per day with S4 Andarine at 50mg a day + Cardarine GW501516 at 20mg per day.  This cycle duration is 8-12 weeks.


You can also bulk by upping your calories 300-500 above maintenance and using Ostarine Ostabolic (MK2866) at 25-50mg per day + LGD4033 Ligandrol Anabolicum 10mg per day + RAD140 Testolone 10mg per day.  This cycle duration also is 8-12 weeks.

General health:

Joint health and nagging injuries can become an issue with those who are frequently in the weight room.  Ostarine Ostabolic (MK2866) can be used at therapeutic dosages of 12.5mg-25mg a day along with Nutrobal MK677 at 12.5-25mg per day to help with your general health.  This cycle duration can be 12-16 weeks.

Anabolic steroid stack:

A lot of users will add Ostarine Ostabolic (MK2866) to their steroid stacks because it will enhance results without adding to side effects.  Those who are cutting with a lot of dry compounds like Winstrol, Masteron, Primobolan, or Anavar will appreciate the joint protections.  While those who are seeking strength and size with steroids like Trenbolone, Testosterone, Deca Durabolin, or Dianabol will appreciate the boost in their cycles without added water retention.   A simple dosage of 12.5mg-50mg per day is ample, and you can stack it throughout your steroid cycle.

You can read more cycling ideas by clicking this link.

During Post cycle therapy

Ostarine Ostabolic (MK2866) has a unique property in that it is not suppressive when used at 4 weeks or less, in conjunction with a dosage of 25mgs or less.  So it makes a fantastic addition to your post cycle therapy (PCT).  Use it with Clomid/Nolvadex at 25mg per day for 4 weeks, and you should also add in a good quality testosterone booster (hcgenerate).   You will notice a tremendous difference when it comes to keeping your hard fought muscle you sweated for during your cycle.

Half-life and detectable times

The half-life of Ostarine Ostabolic (MK2866) is estimated to be 24 hours, which means a dosing schedule of 1-2X per day is ample.

The detectable time is 2-4 weeks and the USADA warns athletes about using it.  If you are tested athlete, using Ostarine Ostabolic (MK2866) is cheating (getting an unfair advantage over your opponents) and you will get caught.  In fact, UFC fighter Jimmy Wallhead was busted for using it earlier this year.  You can read the full story here.

Side effects

There are some rumors that Ostarine Ostabolic (MK2866) aromatizes into estrogen. But that was derived from those using bunk products laced with prohormones.   The reality is there should be no estrogenic, androgenic, or strong suppression from using it.   When used at dosages that exceed 4 weeks or 25mgs per day, users will start to experience some mild suppression.

If this happens a light ‘mini-pct’ is recommended with Hcgenerate ES

Where to buy Ostarine

The United States and credit card processors have started to crack down on the sale of all SARMS. Therefore, it is becoming harder to find a legitimate product.  Domestically, any website still selling Ostarine Ostabolic (MK2866) is likely selling a fake product that is mislabeled.

You can still legally import them but you must make sure you are purchasing from a real company.  I recommend sarms1.com, who is an approved SARMS seller.

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